In 1999, the CDC had a national plan of action to “completely eliminate syphilis” by the year 2005. Although rates of syphilis did dramatically decrease to record lows during that time, we are now experiencing record HIGH rates of congenital syphilis. Some states are having a close to 500% increase in congenital cases. How did we get to this point? In this episode, we will review and summarize 3 key recent publications regarding the rise of congenital syphilis (Journal Women’s Health Issues [Elsevier]– article in press: AJOG Dec 2022; ACOG Clinical Expert Series May 2020) which have resulted in the SCARY STATE of SYPHILIS. We will also review the JH reaction, and provide a clinical pearl regarding the interval restriction between doses of Penicillin G injections, AND we will summarize the time frames permitted to allow a decrease in RPR titers after therapy. Lots of material covered in this episode! 👍