Mina Kimes and Derrik Klassen preview Week 1. They discuss what the absence of Chris Jones and Travis Kelce could mean for the Chiefs against the Lions. They preview 49ers vs Steelers, Bengals vs Browns, Eagles vs Patriots, Dolphins vs Chargers, Packers vs Bears and Cowboys vs Giants. Then Mina and Derrik give their picks for the remaining games on the schedule for Week 1.

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