Please visit answersincme.com/DMC860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, experts in infectious disease discuss the clinical impact of mRNA-based COVID-19 vaccines. Upon completion of this activity, participants should be better able to: Recognize the mechanism of action of available mRNA-based COVID-19 vaccines; Evaluate the clinical impact of available mRNA-based COVID-19 vaccines; and Apply region-specific, patient-centered strategies to optimize uptake of mRNA-based COVID-19 vaccination.