Christian McCaffrey #1 is the easy call, but should he be drafted ahead of Patrick Mahomes in a 2-QB league? Is there any hesitation in putting Dalvin Cook at #2 (5:00)? We take a look at all of the candidates to finish in the Top 5 including Ezekiel Elliott, Aaron Jones and Austin Ekeler along with the usual names. Who has the most upside (8:00)? Who has the most downside (14;00)? What could go wrong with Alvin Kamara? ... The guys give RB3, RB4 and RB5 (20:24). Cook is not #2 in all formats according to Dave. What about Derrick Henry (31:00)? Do we have any concerns about him or are we willing to accept he is a cyborg? ... News and notes (44:00) as we look at the Jaguars and Broncos RB situations, and Jamey reads some funny tweets (49:00)! ... Your emails at fantasyfootball@cbsi.com

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