Marijuana is the most commonly used federally illegal drug in the United States; its use among pregnant and lactating women is on the rise. Is breast-feeding contraindicated with marijuana use? It is difficult to separate marijuana use from several confounding variables, leading to conflicting data in print. Is marijuana use and breast-feeding compatible? A patient friendly article on Parents.com, released on November 23, 2022 seems to imply just that. In this episode, we will review the data on marijuana use during lactation and help clear up the seemingly contradictory outcomes data. Also, we will summarize key position statements from a variety of professional organizations, and find out what data gaps still exist.