Today is episode #24 and it's all about bad genes and how they impact your thyroid function.
There are certain genetic changes, known as single nucleotide polymorphisms or SNP's for short, which can slightly impact certain enzymes in your body.
These genes are very important when it comes to your thyroid because they can impact a set of enzymes known as the deiodinases.
These deiodinases are responsible for activating or inactivating thyroid hormone at the cellular level. And they can be impacted by factors such as your genes, medical conditions, medications, and so on.
There are 3 major deiodinase enzymes:
- D1 - You can consider this an activating enzyme and it is responsible for 30% of T3 in the body.
- D2 - You can consider this an activating enzyme and it is responsible for 70% of T3 in the body.
- D3 - You can consider this an inactivating enzyme which takes T4 and turns it into reverse T3 or rT3.
Certain SNP's impact the function of these enzymes which create conditions in which you may not be able to convert T4 to T3 very well.
DIO2 SNP's and DIO2 SNP's can both impact how your body tolerates certain medications.
You can test for the presence of these enzymes which can help guide your treatment and help you understand which thyroid medication you should be on.
Hey guys!
I'm Dr. Westin Childs and I focus on thyroid health, hormone balance, and weight loss. I write about thyroid disorders, weight loss, insulin resistance, estrogen/progesterone balance on my blog. I truly believe that hormone balance is the key to managing your weight, your mood and your quality of life which is why I'm so passionate about it.
I take a personalized/functional medicine approach to management of conditions. I'm not accepting patients but you can learn more and get plenty of information on my blog!
You can learn more about high-quality supplements that I create (and personally use) here:
https://www.restartmed.com/shop/
You can find more general information on my site here:
https://www.restartmed.com/
If you enjoyed this video please subscribe on youtube or leave a comment on my podcast here: https://itunes.apple.com/us/podcast/dr-westin-childs-podcast-thyroid-weight-loss-hormones/id1141207688?mt=2
This video is not intended to be used as medical advice. If you have questions about your health please consult your physician or primary care provider. Dr. Westin Childs goes to great lengths to produce high-quality content but this is NOT a substitute for medical care.
Do you have any topics or video ideas? Please say so in the comments below!