HBO and The Ringer's Bill Simmons is joined by legendary New York sports radio host Mike Francesa to discuss Jimmy Garoppolo's setup in San Francisco (5:00), Eli Manning's offensive line problem (12:00), Matt Ryan's down year (19:00), picks for Week 16 (32:00), Detroit's quiet season (40:00), and Super Bowl odds (45:00).

Learn more about your ad choices. Visit podcastchoices.com/adchoices