Mike Francesa on the 49ers' Franchise QB, Eli's Next Move, and Week 16 NFL Picks (Ep. 304)

HBO and The Ringer's Bill Simmons is joined by legendary New York sports radio host Mike Francesa to discuss Jimmy Garoppolo's setup in San Francisco (5:00), Eli Manning's offensive line problem (12:00), Matt Ryan's down year (19:00), picks for Week 16 (32:00), Detroit's quiet season (40:00), and Super Bowl odds (45:00).

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