Mycoplasma genitalium is a facultative anaerobic organism which has been associated with cervicitis, endometritis, PID, infertility, susceptibility to HIV, and adverse birth outcomes, indicating a consistent relationship with female genital tract pathology. In 2015, the CDC listed it as an important, yet overlooked, STI. Now, a recently FDA approved test for the bacterium has increased awareness on this sexually transmitted pathogen. In this episode, we will review the microbiology, presentation, and treatment of this pathogen.