Advanced Maternal Age (AMA) has long been associated with adverse obstetrical outcomes. However, is the same true for Advanced Paternal Age (APA)? What is the specific characteristic mutation associated with APA? What does paternal age have to do with chromosomal telomere length and how is that related to cancer in the child? In this podcast, we will review Data from the American College of Medical Genetics regarding APA. This information will be helpful in giving prenatal counseling to couples who present with fathers with age equal to/greater than 40.