Please visit answersincme.com/NFP860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in managing postpartum depression discusses strategies to optimize the use of novel GABAergic neuroactive steroids for the management of patients with postpartum depression (PPD). Upon completion of this activity, participants should be better able to: Recognize the rationale for incorporating the GABAergic neuroactive steroids in the treatment of postpartum depression (PPD); Review the clinical evidence for the novel GABAergic neuroactive steroids in patients with PPD; and Outline patient-centered strategies for personalizing treatment with the novel GABAergic neuroactive steroids.