In 1980s Berkeley, an eccentric chemist and his wife, a self-taught therapist, experimented with MDMA. Their work would kickstart a decades-long campaign to mainstream psychedelics as a therapeutic tool — one that’s coming to a head this month, with a decision due from the FDA.

This episode was reported and produced by Haleema Shah, edited by Lissa Soep and Matt Collette, fact-checked by Laura Bullard, engineered by Andrea Kristinsdottir and Rob Byers, and hosted by Sean Rameswaram. It’s the first in a series supported with a grant from the Ferriss–UC Berkeley Psychedelic Journalism Fellowship.

Transcript at vox.com/today-explained-podcast

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