An evolving burden of evidence supports the theory that a large majority of high-risk ovarian epithelial cancers have a tubal origin. RRS is growing in practice as the preferred option at time of benign Gyn surgery and sterilization. Although RRSO is still preferred in high-risk women (germline mutation carriers), RRS is a possible alternative option, with delayed oophorectomy after age 40. In this podcast, we will review the pathophysiology of epithelial ovarian cancer, its tubal origin, and the role of RRS.
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