Health bosses have warned they cannot guarantee patient safety during strikes by thousands of ambulance workers in England and Wales on Wednesday. Adam is joined by Unison boss Christina McAnea and BBC health reporter Jim Reed to explore how the industrial action could impact the NHS.

And the BBC’s Fergus Walsh celebrates some of the latest medical innovations, including a trial of a personalised cancer vaccine and how a baby's life was 'probably saved' by umbilical stem cells.

This episode of Newscast is presented by Adam Fleming. It was made by Tim Walklate with Miranda Slade, Alix Pickles and Phil Marzouk. The studio manager was Philip Bull. The assistant editor was Louisa Lewis.