1) An index to identify stroke-related versus incidental patent foramen ovale in cryptogenic stroke and 2) Topic of the month: Frontotemporal degeneration. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Bryan Eckerle interviews Dr. David Kent about his paper on using an index to identify stroke-related versus incidental patent foramen ovale in cryptogenic stroke. Dr. Adam Numis is reading our e-Pearl of the week about superior quadrantopia. In the next part of the podcast Dr. Brandy Matthews focuses her interview with Dr. Bill Seeley about clinical presentations and bedside evaluation in frontotemporal degeneration. The participants had nothing to disclose except Drs. Kent, Numis, Matthews and Seeley.Dr. Kent is a consultant for WL Gore Associates and receives research support from the NIH.Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Matthews receives research support from the NIH.Dr. Seeley serves as an editorial board member for Annuals of Neurology; served on the scientific advisory board for Bristol-Myers Squibb; is a consultant for Summer Street Research Partners; received speaker honorarium from Novartis Korea; received research support from the John Douglas French Alzheimer's Disease Foundation, Consortium for Frontotemporal Dementia Research; Tau Consortium, James S. McDonnell Foundation, Alzheimer's Disease Drug Foundation, Association for Frontotemporal Dementia and National Institute on Aging.