This Podcast for the Neurology Journal begins with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns and Dr. Peter Kang interview Dr. Jerry Mendell, Director, Center for Gene Therapy at The Research Institute at Nationwide Children's Hospital about his paper on gene therapy as a potential treatment for LGMD. The podcast concludes with Dr. Erik Ensrud interviewing Dr. Steve Karceski on the topic of translational research efforts. The participants had nothing to disclose.