Daphne Koller, CEO of insitro and cofounder of Coursera, joins Leadership Next to unpack a bold idea: Just as calculus revolutionized our understanding of physics, AI could do the same for biology. In this episode, Koller explains how insitro is blending biology and machine learning to unlock new treatments for diseases like ALS and fatty liver. She also opens up about her leap from academia to entrepreneurship, the ethical challenges of data collection, and why the future of medicine lies in personalized, AI-driven care. Plus, her take on why humans and machines must work in tandem to drive meaningful innovation.