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ELI5 Grapefruit - why no mixing with medications?

ELI5 Explain Like I'm 5: Bite sized answers to stuff you should know about - in a mini podcast
ELI5 Explain Like I'm 5: Bite sized answers to stuff you should know about - in a mini podcast
Episode • Jan 8, 2021 • 7m

What is it about grapefruit that makes it incompatible with so many prescription drugs? What is CYP3A4? What about other similar fruits? Why the name grapefruit if there's no relation to grapes?

 

... We explain like i'm five!

 

Thank you to the r/explainlikeimfive community as always and in particular the following users whose questions and comments formed the basis of this discussion: z-freak, smitten430kittens, 2pam, mistmanx, unusually_awkward, zldfn101, iamlizzy1, capt_groomp, dooks4introvert, notyogrannysgrandkid, femifoodie & tgpineapple

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