This Podcast for the Neurology Journal begins and closes with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interview Dr. John D. England about the new AAN guidelines on distal symmetric polyneuropathy. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Aide's tonic pupil syndrome. The podcast concludes where Dr. Heather Harle interviews Dr. David Herrmann about distal symmetric polyneuropathy and its association with diabetes and impaired glucose intolerance for the Lesson of the Week segment. The participants had nothing to disclose.