1) Diagnosed multiple sclerosis and clinically isolated syndrome and 2) Topic of the month: Mononeuropathies. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Chris Scherer with Dr. Stine Marit Moen about her paper on newly diagnosed multiple sclerosis and clinically isolated syndrome.In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about hung-up reflex. In the next part of the podcast Dr. Ted Burns interviews Dr. John Stewart about ulnar neuropathies. Over the subsequent two weeks, Dr. Burns will interview Dr. Stewart about other common mononeuropathies. The participants had nothing to disclose except Drs. Moen, Fugate and Burns.Dr. Moen has received funding for travel from Biogen Idec; and has received research support from Biogen Idec, the South-Eastern Norway Regional Health Authority, Odd Fellow Research Foundation for Multiple Sclerosis, the Endowment of K. and K.H. Hemsen, and the Endowment of Fritz and Ingrid Nilsen.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Burns receives a stipend as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..