Author Walter Isaacson talks with Recode's Kara Swisher about his new biography of Renaissance artist and inventor Leonardo da Vinci, which he describes has a "culmination" of themes he explored in past books about Ada Lovelace, Ben Franklin and Steve Jobs. Isaacson explains how da Vinci's pursuit of the intersection of art and science made him who he was, and how his life's story can inform our thinking today about innovation and technology. He also dissects the biology of da Vinci's most famous work, the Mona Lisa, and explains why the portrait took 16 years to paint.

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