He was born in Cilicia to a pious family. He left all worldly things and devoted his life to preaching the Gospel of Christ, for which he was arrested in Ancyra by the governor Sacerdos. When he was commanded to worship the idols or suffer torture, Callinicus replied, 'Every torture for my God is as welcome to me as bread to a hungry man.' After harsh torture, the governor had him shod in shoes in which nails had been set pointing upright, and had him driven on foot to the town of Gangra. (The governor was afraid to keep him in Ancyra, since many of the people were turning to Christ through the Saint's example.) On the way, when the soldiers became thirsty, Callinicus prayed to God and brought forth water from a rock. At Gangra he was thrown alive into a furnace. When the fire was out, his dead body was found completely unharmed.