Treatise on the Religious Affections - Part One Negative Sign 2 Great effects on the body certainly are no sure evidences that affections are spiritual; for we see them oftentimes arise from great affections about temporal things, and when religion is no way concerned in them. And if great affections about things purely natural may have these effects, I know not by what rule we should determine, that high affections about religious things, which arise in like manner from nature, cannot have the like effect.