1) Depression in Parkinson disease and 2) Topic of the month: Aphasia. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Russ Swerdlow interviews Dr. Massimo Filippi about his paper on depression in Parkinson disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about five clues to the diagnosis of inclusion body myositis...and...amphiphysin antibody-associated stiff-person syndrome. In the next part of the podcast Dr. Alberto Espay interviews Dr. Keith Josephs about post-stroke aphasias for our Lesson of the Week. Over the next subsequent three weeks, we will highlight primary progressive aphasias. The participants had nothing to disclose except Drs. Filippi, Overman, Espay and Josephs. Dr. Filippi serves on scientific advisory boards for Teva Pharmaceutical Industries Ltd. and Genmab A/S; has received funding for travel from Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, and Teva Pharmaceutical Industries Ltd.; serves on editorial boards of the American Journal of Neuroradiology, BMC Musculoskeletal Disorders, Clinical Neurology and Neurosurgery, Erciyes Medical Journal, Journal of Neuroimaging, Journal of Neurology Neurosurgery and Psychiatry, Journal of Neurovirology, Magnetic Resonance Imaging, Multiple Sclerosis, and Neurological Sciences; serves as a consultant to Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, Pepgen Corporation, and Teva Pharmaceutical Industries Ltd.; serves on speakers' bureaus for Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, and Teva Pharmaceutical Industries Ltd.; and receives research support from Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, Teva Pharmaceutical Industries Ltd., Fondazione Italiana Sclerosi Multipla, and Fondazione Mariani. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee. Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis. Dr. Josephs is funded by R01- DC010367 (PI), the Dana Foundation (PI), and the Morris K. Udall PD Research Center of Excellence NIH/NINDS P50 NS40256 (Co-I).