1) Being diagnosed with multiple sclerosis and how she has focused on living with the disease and 2) Topic of the month: Implementation of genetic testing. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Ms. Janice Dean about being diagnosed with multiple sclerosis and how she has focused on living with the disease. Dr. Sarah Wesley is reading our e-Pearl of the week about spinobulbar muscular atrophy. In the next part of the podcast Dr. Ted Burns interviews Drs. Radhika Dhamija and Christopher Klein about the reporting of sequence variants and also how the interpretability of the data is rapidly changing and what the implications of this change may be. The participants had nothing to disclose except Drs. Burns, Wesley and Klein.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals, Inc.Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Klein serves as an editorial board member of Journal of Peripheral Nerve Society; and receives research support from NIH.