Please visit answersincme.com/EKH860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in oncology discusses frontline immunotherapy-based combination strategies to improve outcomes in patients with advanced biliary tract cancer. Upon completion of this activity, participants should be better able to: Review the rationale for including immunotherapy as a component of a therapeutic approach for patients with advanced biliary tract cancer (BTC); Describe the clinical profiles of immunotherapy plus chemotherapy combinatorial approaches for the treatment of advanced BTC; and Outline practical strategies to enhance evidence-based care of patients with advanced BTC on a combined immunotherapy plus chemotherapy approach.