OpenAI just notched a real biology win: a tiny 4B-parameter model (“GPT-4B-micro”) designed Yamanaka-factor protein variants that jumped lab hit rates from ~0.1% to 30–50% in tests with Retro Biosciences. We unpack how a small, domain-tuned GPT can actually reprogram cells, what partial vs full age reversal could mean, and why this points to personalized longevity. We contrast OpenAI’s approach with Google’s AlphaFold push and outline the road from early results to therapies (think years of trials, roughly 7–12). If you want the fountain-of-youth story grounded in mechanisms, math, and lab-verified results, this episode is it.------🌌 LIMITLESS HQ: LISTEN & FOLLOW HERE ⬇️https://limitless.bankless.com/https://x.com/LimitlessFT------TIMESTAMPS0:00 The Fountain of Youth Unveiled1:17 Understanding Yamanaka Factors5:16 Breakthrough with AI Protein Design8:41 The Implications of Reversing Aging15:12 Aging as a Disease19:04 The Future of AI in Science20:55 The Path to Age Reversal21:50 Exciting Developments Ahead------RESOURCESOpenAI Paper: https://openai.com/index/accelerating-life-sciences-research-with-retro-biosciences/Josh: https://x.com/Josh_KaleEjaaz: https://x.com/cryptopunk7213------Not financial or tax advice. See our investment disclosures here:https://www.bankless.com/disclosures⁠