Despite advances in scientific research, the stomach remains a subject of mystery and intrigue. After all, it’s nearly impossible to ignore its gurgles and growls. Some cultural understanding of the gut has changed too—from an unruly being that must be fed and placated, to a garden ecosystem that is to be nourished in order to flourish.And if you’re a frequent listener of Science Friday, you’re familiar with the gut’s microbiome—the constellation of trillions of microbes thriving in our bodies. And that the stomach has some of the same neuroreceptors as the brain, which has earned it the nickname of the “second brain.”Ira talks with Dr. Elsa Richardson, author of Rumbles: A Curious History of the Gut and co-director of the Centre for the Social History of Health and Healthcare at University of Strathclyde in Scotland. They discuss the changing cultural and scientific understanding of the gut, including the discovery of the enteric nervous system and Victorian-era physician Sir William Arbuthnot Lane’s obsession with curing constipation.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.