Download for FREE today - special Mnemonics Cheatsheet - so you can be SURE that you have that Must Know information down: bit.ly/nursing-memory Outline 6 S's S-Sugar – hyperglycemia S-Soggy Bones – causes osteoporosis S-Sick – decreased immunity S-Sad – depression S-Salt – water and salt retention (hypertension) S-Sex – decreased libido Description Steroids are an effective treatment for asthma, COPD, Crohn's, Lupus and more. However,they have the potential for very serious side effects, which are indicated by the 6 S's. Steroids can be taken by mouth, via an inhaler, topically, or via injection.