This Podcast for the Neurology Journal begins with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interview Dr. Stephen Gomperts about his paper on amyloid deposition in Lewy body diseases. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week. The podcast concludes with Dr. Jonathan Bui interviewing Dr. John Carew about PIB imaging methods for the Lesson of the Week segment. The participants had nothing to disclose.