All platforms / Episode Show Notes: https://livelongerworld.substack.com/p/sapple Sam Apple is the author of Ravenous: Otto Warburg, The Nazis, and the Search for the Cancer-Diet Connection.  Otto Warburg was a Nobel-Prize winning German scientist during the era of Hitler and the Nazi’s and he was the first person to put the metabolic story of cancer on the map. The famous “Warburg Effect” that shows how cancer cells have an increase in glucose uptake even in the presence of oxygen, is named after him. It was a fascinating conversation talking about how the story of cancer research has evolved - how cancer cells eat to the discovery of oncogenes to coming full circle and making the connection between the two, and what the debate still holds in the story. We also talk about how cancer cells take up a lot of glucose, feed on sugar, and the connection between obesity and cancer. I hope you enjoy the conversation!   Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.substack.com/ Find me (Aastha) on Twitter: https://twitter.com/livelongerworld  SUPPORT LIVE LONGER WORLD:  Sign up for Premium Subscriber Transcripts: https://www.livelongerworld.com/premium Patreon: https://www.patreon.com/livelongerworld One-Time support: https://www.paypal.com/paypalme/livelongerworld  SAM APPLE LINKS:  Ravenous book: https://amzn.to/3yT9qpd Website: http://www.samapple.com/ Twitter: https://twitter.com/Sam_Apple1 CONNECT WITH AASTHA, LIVE LONGER WORLD:  Website: https://www.livelongerworld.com/ Twitter: https://twitter.com/livelongerworld Newsletter: https://livelongerworld.substack.com/ Instagram: https://www.instagram.com/longevityfuture/ TIMESTAMPS:  0:00 Cancer as a disease of modern societies  1:27 Otto Warburg & the Cancer-Metabolic Connection  2:27 Warburg’s research on respiration  4:02 Why was cancer skyrocketing in Western societies?  9:17 Warburg Effect: Warburg’s research on cancer cells  15:00 Why do cancer cells take up so much glucose?  17:44 Cancer-Diet Connection  21:44 Cancer, Ketogenic diets & Fasting  23:43 Hibernation of the metabolic story of cancer  27:20 Hitler’s connection with cancer  30:07 Warburg’s arrogance  31:51 Why does cancer need glucose?  38:46 Warburg’s stigma: connecting with Nazi’s  40:51 Is insulin responsible for cancer?  48:00 Science is not immune from politics  50:24 Prostate cancer & obesity  52:13 Pendulum swing in cancer research  54:40 Mitochondria & Cancer Connection  57:07 Nazi’s fixation on cancer Episode Show Notes: https://livelongerworld.substack.com/p/sapple  Live Longer World Season 1 Recap: https://livelongerworld.substack.com/p/season1 Thanks for listening & if you enjoy the episode, let's spread the message on longevity.  You can support my work by sharing, liking, subscribing, leaving a review on Apple podcasts, donating on Patreon, or signing up as a premium member. Aging is universal. Let's unite in this fight.  Stay in good health - Aastha.