Adam and Dr. Drew open the show by going straight to the phones and speaking to a variety of callers including one who suffered a subdural hematoma after being hit by a drunk driver. Adam also presents to Dr. Drew a new syndrome that he believes he has discovered and attempts to get Drew's expert medical opinion behind it to lend credence. The guys also speak to other callers including one with a question about mental illness in his family and another asking for career advice.