Sam Harris speaks with Jennifer Doudna about the gene-editing technology CRISPR/Cas9. They talk about the biology of gene editing, how specific tissues in the body can be targeted, the ethical implications of changing the human genome, the importance of curiosity-driven science, and other topics. Jennifer A. Doudna is a professor in the Chemistry and the Molecular and Cell Biology Departments at the University of California, Berkeley, investigator with the Howard Hughes Medical Institute, and researcher in the Molecular Biophysics and Integrated Bioimaging Division at the Lawrence Berkeley National Laboratory. She is internationally recognized as a leading expert on RNA-protein biochemistry, CRISPR biology, and genome engineering. She is the author (with Samuel Sternberg) of A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution.