My guest today is Dr. Bjorn Schumacher whose work focuses on the central role of DNA damage in the aging process. We discussed DNA damage accumulation with age, how DNA repair mechanisms play a role, how DNA damage in the reproductive cells can tell us a lot about aging, human fertility and reproductive capacity. We also discussed the role of p53 in cancer suppression, a new biological age clock being developed in his lab and how we should protect our skin from aging and thereby control DNA damage.  A lot of us have heard about the link between DNA damage and aging and this conversation really dives into it.   All platforms / Episode Show Notes: https://livelongerworld.substack.com/p/bschumacher  Find the previous podcast episodes & subscribe to be notified: https://www.livelongerworld.com/podcast  Sign up for Premium Subscriber Summarized Show Notes on Key Points: https://www.livelongerworld.com/premium  Support on Patreon: https://www.patreon.com/livelongerworld One-Time support: https://www.paypal.com/paypalme/livelongerworld  DR. BJORN SCHUMACHER LINKS:  Lab Website: https://www.cecad.uni-koeln.de/research/principal-investigators/prof-dr-bjoern-schumacher Twitter: https://twitter.com/schumacherbj Author of the book: The Mysteries of Human Aging: Surprising Insights from a Science That's Still Young: https://amzn.to/3LyR3JU LIVE LONGER WORLD LINKS:  Website: https://www.livelongerworld.com/ Twitter: https://twitter.com/livelongerworld Newsletter: https://livelongerworld.substack.com/ Instagram: https://www.instagram.com/longevityfuture/ Patreon page: https://www.patreon.com/livelongerworld Podcast All Platforms: https://anchor.fm/livelongerworld YouTube: https://www.youtube.com/c/LiveLongerWorld Apple Podcasts: https://apple.co/3eZAoAp Spotify: https://spoti.fi/3eZB6O5 Google Podcasts: https://bit.ly/3HN0keG Premium Subscriber Benefits: https://www.livelongerworld.com/premium TIMESTAMPS:  0:00 Live Longer World Intro  0:30 Bjorn Schumacher Intro  1:22 DNA Damage as Central to the Aging process  3:37 DNA repair with age  8:39 Premature aging; 2 distinct forms of DNA damage  14:15 How does an aging human survive with DNA damage & tamp down cancer?  18:20 Stress to reproductive cells builds up immunity in the body  24:41 Female reproduction, Menopause & DNA repair  27:46 p53 and it’s role in DNA repair  35:13 BiT Clock: New Biological Age Clock  43:59 Skin Aging and DNA damage  48:06 Stress in the intestine / gut can alter the chromosome  53:00 Germ cells are immortal For links to DR. Bjorn Schumacher research discussed: https://livelongerworld.substack.com/p/bschumacher Want Summarized Notes on Key Points Discussed in the Podcast?  Gain access by signing up as a premium subscriber. Your contribution supports my work the advancement of longevity science! Key points summarized in the show notes for premium subscribers include: The central role of DNA damage in the aging process What happens to our body’s DNA repair mechanism with age? DNA Damage in the germ cells (reproductive cells) promotes stress resistance in the body The role of p53 in suppressing cancer and in the DNA repair process Learn more: https://www.livelongerworld.com/premium Thanks for listeni