Insights derived from clinical trials is what pushes medicine forward. And when a trial is conducted in error – or sometimes even fraudulently – the repercussions can reach far and wide. Richard Van Noorden is an editor for the journal Nature, and he joins Krys Boyd to talk about how bias, error and, yes, even fraud, infect clinical trials – and what can be done to clean them up. His recent article is headlined “Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed?”